Coyotillo poisoning in goats is caused by ingestion of coyotillo (Karwinskia humboldtiana), a woody shrub which is toxic to animals and humans. Most cases of poisoning occur in the winter, when plants are abundant with fruit and other forage.
Consumption of as little as 0.3% of the goat’s body weight of the fruit is lethal. Losses of more than 1,000 goats caused by coyotillo poisoning have been reported on Texas ranches. The plant contains polyphenolic compounds which affect the goat's nervous system.
