Veterinary advice should be sought before applying any treatment or vaccine.

Pemphigus Foliaceus

Pemphigus foliaceus is a rare autoimmune disease of the skin that can affect humans, goats, horses, cats and dogs. It affects all ages of goats, ranging from 1 month to seven years of age.

Symptoms

Skin lesions and hair loss on lips, face and neck, ears, and/or feet

Generalized, non-pruritic exfoliative dermatitis

Abundant scale-crust

Pustules affecting haired skin

Randomly scattered coalescing, circular patches of hair loss

Diagnosis

History
Clinical signs
Skin biopsy of lesions
Histology
Direct immunofluorescence testing

Treatment Options

Treatment Type	Details
Systemic glucocorticoids	Prednisone 1 mg/kg IM twice daily for 7-10 days, then alternate morning therapy at a reduced dosage
Corticosteroid injection	Administered IM once every 2 months

References

Janzen AM, Wiles D, Myers S, Marqués FJ. Pemphigus foliaceus in a juvenile Cashmere goat, and outcome after prednisolone and methylprednisolone therapy. Can Vet J (2011)
Cornish J, Highland M. Successful treatment of juvenile pemphigus foliaceus in a Nigerian Dwarf goat. J Am Vet Med Assoc. (2010)
Pappalardo E, Abramo F, Noli C. Pemphigus foliaceus in a goat. Vet Dermatol. (2002)
Valdez RA, Gelberg HB, Morin DE, Zuckermann FA. Use of corticosteroids and aurothioglucose in a pygmy goat with pemphigus foliaceus. J Am Vet Med Assoc (1995)

Pemphigus Foliaceus

Symptoms

Diagnosis

Treatment Options

References

GoatDVM.com

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